|
Usher Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We used 3 fluorescently labeled short tandem repeat (STR) markers for each of the known autosomal recessive nonsyndromic (DFNB) and Usher syndrome (USH) locus to perform a linkage analysis of 243 multigenerational Pakistani families segregating prelingual hearing loss.
|
23770805 |
2013 |
|
Turner Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In addition, Turner syndrome (45, X0) DNA can be distinguished from normal male DNA because it fails to amplify a Y-chromosome specific PCR marker yet contains only a single dose of X-specific STR markers.
|
8490622 |
1993 |
|
Triploidy syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Of the two discordant results, a 69,XXX polyploidy was missed by CNV-Seq, although supporting STR marker analysis confirmed the triploidy.
|
25767059 |
2015 |
|
Thyroid Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
As a demonstration of the utility of the genotyping platform in whole-genome scans, we have replicated and refined a linkage region on chromosome 2p for chronic mucocutaneous candidiasis and thyroid disease, previously identified using a panel of microsatellite (STR) markers.
|
14993208 |
2004 |
|
Superficial ulcer
|
0.010 |
Biomarker
|
disease |
BEFREE |
In total, 223 proteins were identified.After treatment with EGCG and CHX gels, proteins with potential functions to protect against caries and erosion such as PRPs, calcium-bind proteins and Statherin were increased.
|
28622550 |
2017 |
|
Spinal Muscular Atrophy
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Here, for the first time, we report on the heterozygosity analysis of five STR markers (D5S1408, D5S1417, D5S610, D5S629 and D5S637) flanking to SMA gene region, to examine their applicability in the PGD for SMA disease.
|
23132709 |
2013 |
|
Spastic Paraplegia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Linkage was examined using simple tandem repeat (STR) markers located near the 5 loci for familial SPG on chromosomes Xq28 (SPG1), Xq21.3-q22 (SPG2), 2p21-p24 (SPG4), 14q12-q23 (SPG3) and 15q11.1 (SPG6).
|
8946171 |
1996 |
|
Skin Erosion
|
0.010 |
Biomarker
|
disease |
BEFREE |
In total, 223 proteins were identified.After treatment with EGCG and CHX gels, proteins with potential functions to protect against caries and erosion such as PRPs, calcium-bind proteins and Statherin were increased.
|
28622550 |
2017 |
|
Schizophrenia
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
This article-one in a series that describes the results of a genome-wide scan with 459 short-tandem repeat (STR) markers for susceptibility loci in the NIMH Genetics Initiative schizophrenia sample-presents results for African-American pedigrees.
|
9674972 |
1998 |
|
Schizophrenia
|
0.020 |
Biomarker
|
disease |
BEFREE |
To determine if there are common genes that contribute to the susceptibility for schizophrenia, first-stage genome-wide scan was carried out by genotyping 417 short-tandem repeat (STR) markers in 338 individuals from 130 families with 148 affected sib-pairs identified at 16 sites nationwide in Japan.
|
12815734 |
2003 |
|
Rheumatoid Arthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
In the current study we aimed to physically link the RA-associated marker with the corticotropin-releasing hormone (CRH) candidate gene, and to examine the genomic region for additional short tandem repeat (STR) genetic markers in order to clarify the association with RA.
|
11817611 |
2002 |
|
Retinitis Pigmentosa
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Exclusion studies were performed with short tandem repeat (STR) markers flanking reported autosomal recessive RP loci.
|
20538656 |
2010 |
|
Primary malignant neoplasm of lung
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In this study, 75 lung cancer tissue samples were examined to evaluate the reliability of various STR markers.
|
29154002 |
2018 |
|
Primary congenital glaucoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Fluorescence Labeled Multiplex-PCR was used to genotype 12 short tandem repeats (STRs) within GLC3C region and transmission disequilibrium test (TDT) was used to analyze the association between PCG and these STR markers.
|
21622161 |
2011 |
|
Prader-Willi Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
To establish a linkage analysis method for Chinese patients, this study identified a useful set of STR markers in the typical PWS deletion and adjacent area, for linkage analysis in two Chinese families with PWS offspring.
|
17945167 |
2007 |
|
Posterior subcapsular cataract
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Here we report linkage of autosomal dominant "progressive childhood posterior subcapsular" cataracts segregating in a white family to short tandem repeat (STR) markers D20S847 (LOD score [Z] 5.50 at recombination fraction [theta] 0.0) and D20S195 (Z=3.65 at theta =0.0) on 20q, and identify a refined disease interval (rs2057262-(3.8 Mb)-rs1291139) by use of single-nucleotide polymorphism (SNP) markers.
|
17701905 |
2007 |
|
Polycystic Kidney, Autosomal Dominant
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In this study, we used fluorescent short tandem repeat (STR) markers to perform linkage analysis in six unrelated ADPKD families.
|
12440087 |
2002 |
|
Pneumocystis jiroveci pneumonia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Genotyping was performed using six already validated short tandem repeat (STR) markers on 249 samples (median: 17 per centre interquartile range [11-20]) from PCP patients of 16 European centres.
|
28705464 |
2017 |
|
Neuropathy
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Hereditary neuralgic amyotrophy (HNA) is an autosomal dominant recurrent neuropathy mapped to a 4-cM interval on chromosome 17q25 between the short tandem repeat (STR) markers D17S1603 and D17S802.
|
10610718 |
1999 |
|
Nasal Polyps
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Quantitative RT-PCR and immunohistochemical staining confirmed the differential expression of all except statherin in NP tissue.
|
15480316 |
2004 |
|
myeloblastosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Three sets of highly expressed candidate genes-distal-less homeobox 6 (DLX6) for E-ACC; protein keratin 16 (KRT16), SRY box 11 (SOX11), and v-myb avian myeloblastosis viral oncogene homolog (MYB) for M-ACC; and engrailed 1 (EN1) and statherin (STATH), which are common to both E-ACC and M-ACC)-were further validated at the protein level.
|
26953815 |
2016 |
|
Miscarriage
|
0.020 |
Biomarker
|
disease |
BEFREE |
Quantitative fluorescent polymerase chain reaction analysis of maternal and POC DNA for short tandem repeat (STR) markers was used to both monitor maternal cell contamination and confirm the chromosomal status and sex of the miscarriage tissue.
|
25767059 |
2015 |
|
Miscarriage
|
0.020 |
Biomarker
|
disease |
BEFREE |
Multiplex and simple QF-PCR assays have been performed on 160 miscarriage and 34 parental DNA samples analysing specific short tandem repeat (STR) markers for chromosomes 2, 7, 13, 15, 16, 18, 21, 22 and X.
|
15760965 |
2005 |
|
Migraine Disorders
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Our laboratory has previously reported association of migraine with a promoter STR marker in the dopamine beta hydroxylase (DBH) gene.
|
19219470 |
2009 |
|
Mammary Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
We have analyzed a panel of 85 breast tumor/normal tissue pairs with 21 PCR-based short tandem repeat (STR) markers located at 17q12-qter to more precisely define regions of allelic imbalance and to determine their relation to clinical parameters.
|
9408751 |
1997 |